The Innovation Driven Entrepreneurship Center (IDE), by the University of Thai Chamber of Commerce targets to create new entrepreneurs with exponential growth in global scale. IDE Center officially partnered with MIT Regional Entrepreneurship Acceleration Program (MIT REAP), authorized by Massachusetts Institutes of Technology (MIT), United States of America. The joint project has been specially developing entrepreneurs in nationwide and filter through innovation-driven entrepreneurship. The IDE Center is established to achieve in creating ecosystem amongst entrepreneurs that drives by innovations as we called “IDE Ecosystem”. The core mechanism consists of 5 partners including educational sector, public sector, private sectors, entrepreneurs cluster, corporate enterprises and financial institutes. Altogether, ecosystem will be wheeled up as potential key driver of Thailand’s economics.